Rabbit Anti-PLAC8 Polyclonal Antibody 

NUMBER:YB75589 

Size:50ul 

Host:Rabbit 

Target Protein:PLAC8 

IR:Immunogen 

Range:51-115/115 

Concentration:1mg/ml 

Applications:IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 

Cross Reactive Species:(predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Chicken,Dog,Horse) 

Clonality:Polyclonal 

Isotype:IgG 

Entrez Gene:51316 

Swiss Prot:Q9NZF1 

Source:KLH conjugated synthetic peptide derived from human PLAC8 :51-115/115 

Purification:affinity purified by Protein A 

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 

Background:PLAC8 is a 115 amino acid protein belonging to the cornifelin family that is expressed athigh levels in plasmacytoid dendritic cells and other organs of the immune system including lymph nodes, spleen, bone marrow and peripheral blood leukocytes, with lower expression in appendix, thymus andfetal liver. Human PLAC8 shares 83% homology with murine PLAC8, where it has been identified inplacenta from 9.5-18.5 days postcoitum. The gene encoding PLAC8 maps to human chromosome 4, which represents approximately 6% of the human genome and contains nearly 900 genes. Notably, theHuntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease,is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated withthanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is alsotied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease